Cleaning validation is a procedure of establishing evidence that cleaning processes for manufacturing equipment prevent product contamination
In recent years, laboratories have been investigating new alternatives to eliminate or avoid animal testing of cosmetic and medical products.
The correct adhesion of a transdermal patch to skin throughout the established time of use is key to guarantee the effective administration of the dose declared in the prescribing information.
Could the 3D printer be a key aspect for personalized medicine? What are its advantages and the challenges it has to face to make this happen?
The production of transdermal patches is a continuous and artisanal process that consists of 3 stages that reflect how delicate and specific is the production of this niche pharmaceutical form. Let´s review it!
In this article we share the most important advantages that transdermal patches have over other dosage forms and routes of administration.
Far away, in 1979, the first transdermal patch to reach the market, produced under an industrial controlled process and backed by clinical studies, was launched in US under the brand name TransderScop®.
The Latin American surveillance health authorities have made progress year after year with respect to the requirements of product registration in general, seeking the best balance between the safety of its inhabitants, the efficacy of the products and the economic reality of each country.
Transdermal drug delivery systems, also named as “patches”, are controlled release dosage forms designed to deliver a therapeutically effective amount of drug through the skin during the time of application of the product, which may vary between 9 h (methylphenidate) to 148 h (buprenorphine).